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4 reported observational data from Shanghai Sixth Peoples Hospital, China, showing that, with adequate treatment duration, GLP-1 agonists may have disease-modifying effects in patients with KOA with comorbid Type 2 diabetes, potentially mediated by weight loss

**Offer ends 12/31/26

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Retatrutide (LY3437943) is an investigational triple-hormone receptor agonist developed by Eli Lilly that targets the GIP, GLP-1, and glucagon receptors simultaneously

It is synthesized primarily in the cytosol of mammalian cells, with the highest concentrations found in the liver