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While dry mouth is a less common side effect of semaglutide compared to gastrointestinal issues, approximately 5-10% of users report this condition
It does not smell off
A recent meta-analysis including 6 trials and 4744 participants indicated that semaglutide reduced DBP by 2.5 mmHg in obese patients without DM [39]
These alterations compromise the molecular machinery necessary for successful embryo implantation
Regulatory bodies may require a dedicated cardiovascular outcomes trial before or after full approval is granted consistent with the precedent set for other agents in this class though the precise regulatory requirements will be determined by the MHRA and EMA based on the totality of evidence submitted
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