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Using naltrexone to cut back on drinking isnt new, says Sarah Wakeman, a senior medical director for substance use disorder at Mass General Brigham

Weight management is also important after a cancer diagnosis

On January 4, 2026, Novo Nordisk's data exclusivity for semaglutide expired in Canada

Combining appetite suppressants that work through different mechanisms could theoretically enhance weight loss, but it could also increase the risk and severity of side effects from both medications simultaneously

More serious risks include pancreatitis, gallbladder disease, acute kidney injury (particularly with dehydration), hypoglycemia (when combined with insulin or sulfonylureas), and thyroid C-cell tumors in animal studies