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It should also be noted that arsenic is documented as an inhibitor of glutathione reductase and the seleno-enzymes glutathione peroxidase and thioredoxin reductase
His team is best known for identifying MOTS -c, which has been called an exercise mimetic: it activates cellular pathways that are usually turned on during exercise
Reduced glutathione neutralizes the positively charged intruders by donating electrons
Dent Clin
For this reason, it was thought that the enzyme played an important role in ammonia detoxification, because since high [NH 4 + ] are toxic, this equilibrium position would be physiologically important
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