This was a great addition to my Tirzepatide Injection I didnt notice a huge difference, but I started this with the Tirzepatide shot
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When NNMT activity is high, less nicotinamide enters this pathway and intracellular NAD+ levels fall
Results: After 12 weeks of GLP-1 RA therapy, the Control group showed significant reductions in SDNN, SDANN, RMSSD, pNN50, and lnHF, together with increases in lnLF and the lnLF/lnHF ratio, whereas no significant within-group changes in HRV indices were observed in the DAPA group