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The mechanism of ferroptosis involves the highly expressed polyunsaturated fatty acids (PUFAs
First, we investigated whether TfR1 levels were altered with RSL3 in PTC cells, as TfR1 has been shown to be a better marker of ferroptosis 22
LPO is a free radical reaction process, which is triggered by the formation of OH radicals (Fe 2+ -dependent Fenton reaction) from H 2 O 2 combined with the production of lipid radicals, leading to the destruction of polyunsaturated fatty acids (PUFAs) [71]
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In such a case, the health care professional may also prescribe injections or supplements of B12.Vitamin B12 is essential for nerve function and red blood cell formation
