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Adjust portions to your individual calorie needs as advised by your healthcare provider or dietitian

Wu CY, Iskander C, Wang C, Xiong LY, Shah BR, Edwards JD, et al

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1:1 propensity-score matching

The screening identified six key pharmacophoric features in the co-crystallized structure of PDE10A (PDB ID: 5UWF) and the ligand 16d, which included one hydrogen bond acceptors (HBA) interacting with Q726, an aromatic ring (AR) represented by the thiophene moiety, and four hydrophobic areas (HA) represented by phenol, sulfide, and fluorine groups