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Farrer, Boston University School of Medicine, USA The article belongs to the special issue Reactive Oxygen Species (ROS) in Pathophysiological Conditions Since obesity is one of the main factors in the development of insulin resistance (IR) and is also associated with increased oxidative stress (OxS) rate, this study aims to review the published literature to collate and provide a comprehensive summary of the studies related to the status of the OxS in the pathogenesis of obesity and related IR

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The hypothesis