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Similarly, the SURMOUNT trials evaluating tirzepatide for weight management did not systematically assess sexual health outcomes, leaving a significant gap in our understanding of this medication's impact on ED

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Semaglutide reduced proteins involved in vascular inflammation and remodeling, including NT-proBNP, angiopoietin-2 (ANGPT2), thrombospondin-2 (THBS2), macrophage scavenger receptor-1 extracellular domain (MSR1), and tenascin-C (TNC), suggesting vascular benefits beyond weight loss and glycemic control

Conjunctivitis was the most frequently reported eye disorder

The Medicines and Healthcare products Regulatory Agency (MHRA) has approved its use, and it is increasingly prescribed for glycaemic control