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Clinical Professor, Faculty of Medicine, University of Montreal
As an extension of the above, the brains high metabolic rate and oxygen consumption make it vulnerable to oxidative stress, which can lead to aging and neurodegenerative diseases like Alzheimers and Parkinsons Disease
For example, Curcumin oral bioavailability in humans is less than 1% due to rapid glucuronidation and sulfation in the intestine and liver (164)
Effect of iron on renal tubular epithelial cells
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