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Inhibiting Mcl-1 with an antisense oligonucleotide induces cell death in acute myeloid leukemia cells

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6 Neurohormonal Mechanisms GLP-1RAs may modulate the activity of the autonomic nervous system by shifting the balance away from sympathetic overactivation towards parasympathetic tone

Over the past decades, several randomized clinical trials (RCTs) have shown that GLP-1 RAs improve cardiovascular outcomes in patients with type 2 DM (T2DM) who have established CVDs or are at risk, as well as in individuals with CKD [16,17,18,19]