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Tirzepatide (sold under the brand name Mounjaro ) is a medication that helps with weight loss by mimicking two key hormones involved in appetite regulation and blood sugar control: GLP-1 (Glucagon-Like Peptide-1) receptor agonist This hormone slows down stomach emptying, reduces appetite, and increases the feeling of fullness after eating
Who Is at Higher Risk: Genetic and Clinical Factors Certain genetic variations in GLP-1 receptor signaling and metabolic genes may predispose some individuals to stronger initial fatigue responses
This is likely due to the rapid weight loss affecting hormone levels rather than a direct effect of the medication itself
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