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Prog Lipid Res 49:6175

AOD-9604 will not overcome a caloric surplus

But Reuters reported that stopping for as little as six months erased much of that protection, raising risk by 4 percent compared to continued use. Washington University likewise said an interruption of six months before resuming treatment still reduced the cardiovascular benefit, leading to a 4 percent to 8 percent increase in risk compared to continuous use

Published online December 21, 2024

This mailbag episode tackles tough questions about medication effectiveness, unexpected side effects, and the complex realities of treating metabolic dysfunction