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However, while it is evident that DPP-4 has the potential to influence glycaemic control, its overall significance for the normal physiological regulation of glucose homeostasis in humans and its role in the pathogenesis of metabolic disease remain to be established

This may cause the battery to leak and the reaction with air may cause the chemicals to ignite, resulting in a fire

Neither peptide is metabolized through cytochrome P450 pathways, so pharmacokinetic interactions are unlikely, though this has not been formally studied

Only injectable GLP1RAs were considered eligible (exenatide, lixisenatide, liraglutide, albiglutide, dulaglutide, semaglutide)

The delivery concept is plausible, and small human studies support biological delivery from tested formulations