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The dual-receptor mechanism of tirzepatide activates both GLP-1 and GIP pathways, potentially amplifying appetite suppression and metabolic effects
The tirzepatide doses of 10 and/or 15 mg demonstrated superiority compared to placebo for the coprimary endpoints percentage body weight reductions from baseline at week 72 and the proportion of patients achieving 5% body weight reduction at week 72
It cannot be stressed enough that obesity is a disease, and the disease is associated with a higher risk of certain other conditions, compared with people who are considered a healthier weight, says Samantha Cassetty, a registered dietitian based in New York City and the coauthor of Sugar Shock
University of PittsburghSally E
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