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In lab experiments, they found that both drugs did their job, but KBP-336 was more powerful and leaned more towards activating one of the sensors over the other
DHODH is significantly downregulated at the mRNA level in response to 5FU treatment (RNA sequencing (RNA-seq) data
doi:10.1016/j.ctim.2019.02.014
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Pathogenic variants in SQOR encoding sulfide:quinone oxidoreductase are a potentially treatable cause of Leigh disease
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