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AGT is present in the proximal tubule and concurrent increases in AGT-mRNA/protein in renal tissue homogenates has been explained as indicating that transcriptional activation of the AGT gene would be responsible for renal ANG II increase
Shayla Lost 64 lbs I went from 204lbs and now im down to 140lbs using Tirzepatide
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In MASH, a phase 2 trial including patients with moderate or severe fibrosis evidenced that tirzepatide achieved a MASH resolution of up to 62% at 52 weeks, without worsening of fibrosis [142]
Patients should maintain a symptom diary documenting the timing, severity, and duration of side effects, along with dietary intake and other relevant factors
