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Periodic blood tests for growth hormone, IGF-1, sex hormones, metabolic markers, and cardiovascular risk factors help guide dose changes and identify adverse trends

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As an example, GSH depletion has been shown to promote pro-inflammatory microglial phenotypes and amplify astrocyte-microglia crosstalk (Vilhardt et al., 2017)

Around 50% of people lose at least 5% of their starting weight within 6 months