average weight loss on tirzepatide in first 3 months A real-world study of for adults without diabetes mellitus 3 months vs. 6 months

Blood sugar is stable

In this population of adults with overweight or obesity, use of tirzepatide was associated with significantly greater weight loss than semaglutide. Last week researchers reported significant but tentative findings that patients taking semaglutide were four times more likely to be diagnosed with an eye condition known as non-arteritic anterior ischemic optic neuropathy (naion)

Epub 2020 Nov 18

A number of digital health companies including Ro, Noom, 23andMe and WeightWatchers also offer access to compounded GLP-1 medications

Without direct tissue quantification, it is unknown if the CNS exposure was high, or if the large systemic dose simply compensated for low anatomical delivery efficiency across the nasal mucosa