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116,153 For example, the third-generation BCR-ABL inhibitor ponatinib forms novel hydrophobic and van der Waals interactions with the T315I-mutated ABL kinase, providing precise inhibition of resistance in acute lymphoblastic leukemia
The authors established FOXO4-DRI as a first-in-class senolytic peptide tool for cellular senescence research, with mechanistic selectivity grounded in the elevated FOXO4-p53 interaction in senescent versus non-senescent cells
Literature PubMed publications on BPC-157 alone
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