Harness the antioxidant power of Glutathione, energize with Vitamin B-12, and NAD+
Results from a phase 2 study support that PXL065 improves liver fat content, procollagen III N-terminal propeptide, and NAFLD fibrosis score, as well as histological parameters, including NAS and fibrosis, with a favorable safety profile
But an association seen in groups of patients is a long way from a prediction about any one person, and the authors note that the causes of a high B12 are multiple and its consequences not clearly established
Important safety considerations include risks of medullary thyroid carcinoma (contraindicated in patients with MEN2 or family history of MTC), pancreatitis, gallbladder disease, acute kidney injury with severe gastrointestinal adverse effects, and potential diabetic retinopathy complications in patients with type 2 diabetes
According to the American Diabetes Association , its been a first-choice treatment for type 2 diabetes for decades