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Switching between cagrilintide and retatrutide Some researchers start with one compound and switch to the other based on their experience
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[1] [3] These include: Nausea and vomiting (particularly during dose escalation) Diarrhoea Reduced appetite and fluid intake When these symptoms are severe or prolonged, they can lead to dehydration , which reduces renal perfusion and may precipitate acute kidney injury (AKI)
Comparative real-world data from clinics using both medications suggests that side-effect severity correlates more strongly with dose-escalation speed and individual gastrointestinal baseline than with medication choice alone
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