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For most patients, high-dose oral B12 supplements are as effective as intramuscular injections

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Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial [published correction appears in Lancet

Compounds that effectively reduce alcohol use while producing more modest effects in other domains may represent leading candidates for clinical development

Many formulations also incorporate L-carnitine (to support fatty acid oxidation), B-complex vitamins , and MIC blends (methionine, inositol, choline)