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No controlled data exists to support a specific timing advantage
Because of this short half-life, most clinical protocols call for daily dosing or, in some cases, twice-daily dosing to maintain consistent levels in the body throughout the treatment period
Acne: In some cases, B12 injections have been linked to breakouts
PMID 28032115
They're especially beneficial for individuals with known vitamin deficiencies, those on restrictive diets, athletes seeking faster recovery, and anyone experiencing chronic fatigue or low energy
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