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Through its reactive sulfhydryl group, GSH participates in oxidation-reduction reactions, thiol-disulfide exchange processes, and cofactor-dependent enzymatic mechanisms
Its role is especially crucial in the induction of ferroptosis, an iron-dependent cell death pathway, positioning it as a context-dependent modulator of cancer progression, neurotoxicity and neurodegeneration
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68, doi:10.1186/1750-1172-7-68
Counsel women of childbearing potential regarding the potential risk to the fetus from topiramate exposure, and consider alternative therapeutic options in women who are planning a pregnancy
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