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Low levels of SAM in the liver prevent the formation of VLDL and cause lipid accumulation in the liver, often known as fatty liver
As such, perhaps the ability of the juvenile Cntnap2 KO mice to respond acutely to the MC4R agonist may be secondary to a critical time point in development with increased responsiveness to oxytocin stimulation and reward behaviors based on oxytocin receptor distribution
Less serious side effects may also occur, including nausea, vomiting, diarrhea and constipation, according to Harvard Health
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