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Finally, we used to model to show how the observed metabolic profile of Down syndrome could arise from trisomy 21 and moderate oxidative stress and how the observed metabolic profile of autism patients could arise from high oxidative stress and increased adenosine concentration

10.1016/0009-8981(73)90423-3 62 de BariL.FaviaM.BobbaA.LassandroR.GuerraL.AtlanteA

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For continuous variables, group comparisons of efficacy endpoints were tested using an independent two-sample t test or Wilcoxon rank-sum test, whereas within-group comparisons were tested using the paired t test or Wilcoxon signed test

Reduced expression of connective tissue growth factor (Ctgf/ccn2) mediates collagen loss in chronologically aged human skin