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Figure 1 Dysfunction of the UPS is associated with many neurological diseases including Alzheimers disease (AD), Amyotrophic Lateral Sclerosis (ALS), neuronal degeneration, remodeling and regeneration after spinal cord injury (SCI), Parkinsons disease (PD), Transmissible Spongiform Encephalopathies (TSE), and Huntingtons disease (HD

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