It is used only where a provider judges it appropriate after reviewing your history, with candidacy assessed individually and the regulatory position explained to you directly before you decide
GLP-1RAs and SGLT2 inhibitors also have pleiotropic effects, including blood glucose-dependent and -independent mechanisms, effects on the reninangiotensinaldosterone system and favourable effects on left ventricular and renal functions [35, 36]
[5] Additionally, GLP-1 receptor agonists carry risks of gallbladder disease (cholelithiasis, cholecystitis) and pancreatitis that may present with abdominal pain and other gastrointestinal symptoms
not for human or veterinary application References Francis G.L
9 Thomas, M.K., et al., Dual GIP and GLP-1 Receptor Agonist Tirzepatide Improves Beta-cell Function and Insulin Sensitivity in Type 2 Diabetes