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Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial

Local and Systemic Action : Can be used site-specifically to stimulate localized growth or systemically to improve total-body recovery

264 In solid tumors, proteasome inhibitors can induce YAP/TAZ activation by inactivating the Hippo pathway, thereby promoting tumor cell proliferation and resistance to apoptosis and ultimately driving therapeutic resistance

Extracellular molecular signals shaping dendrite architecture during brain development

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