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Eur J Endocrinol 153: 747-753 Duranay M, Akay H, Yilmaz FM, Senes M, Tekeli N, et al

There are however, many patients who do not suffer from any of the above historical side effects but rather have dermatologic mild responses like slight swelling or redness around the injection site

GRAS food ingredient note AOD-9604 was self-affirmed as Generally Recognized As Safe (GRAS) by an industry expert panel for limited food-ingredient use based on the Phase 1 and Phase 2 safety data

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Furthermore, a dose reduction in insulin or the sulfonylurea may be necessary to avoid hypoglycemia