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Step 3: The Showstopper (Optional) For some patients, a grand finale may be in order

4 We suggest classifying HE according to its severity, as covert (MHE and grade I of the West Haven Criteria [WHC]) and overt (starting at grade II of the WHC)

Incorporating biologics and additional OSA treatments could improve patient identification accuracy

Of course, thats not always possible

Additionally, subgroup analyses were conducted to evaluate potential effect modification by sex, age, BMI, smoking status, and antihypertensive medication use, with P-values for interaction calculated to determine statistical significance