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Pinch a fold of skin and fat, insert the needle at 90 degrees into the center of the fold, and hold the pinch throughout the injection
In Phase I clinical trials, PGN-EDO51 showed good safety, tolerability, and efficacy, and Phase II trials are ongoing
Plasma nonesterified fatty acid (NEFA) was measured using a NEFA-C assay kit (WAKO, Osaka, Japan)
However, darker skin types must use it with caution, since skin lightening can occur
This isnt about restriction or extremes
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