The previously used antischistosome drugs PAT and OPZ inhibited recombinant schistosome TGR, suggesting that the enzyme may already have served as a target protein for antischistosomal therapy
Reda A, Veys K, Kadam P, Taranta A, Rega LR, Goffredo BM, Camps C, Besouw M, Cyr D, Albersen M, Spiessens C, de Wever L, Hamer R, Janssen MCH, DHauwers K, Wetzels A, Monnens L, van den Heuvel L, Goossens E, Levtchenko E (2021) Human and animal fertility studies in cystinosis reveal signs of obstructive azoospermia, an altered blood-testis barrier and a subtherapeutic effect of cysteamine in testis
Majumder, J., & Minko, T
The probability of survival was estimated using the Kaplan-Meier method
Copper homeostasis and cuproptosis in health and disease