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Johns Wort, and other serotonergic agents
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The expectation is that ex-China licensing partners will build the thicket around the molecule after license
Abbreviations BP: Blood pressure CI: Confidence interval CIMT: Carotid intima-media thickness eGFR: Estimated glomerular filtration rate HbA1C: Hemoglobin A1c HDL: High-density lipoprotein cholesterol ICA: Internal carotid artery L-C: L-carnitine LDL-C: Low-density lipoprotein cholesterol Lp(a): Lipoprotein (a) MetS: Metabolic syndrome MI: Myocardial infarction MPH: Maximum plaque height NSAIDs: Nonsteroidal anti-inflammatory drugs SAEs: Serious adverse events TMAO: Metabolites such as trimethylamine oxidase TPA: Total plaque area TPV: Total plaque volume WC: Waist circumference References Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WP, Loria CM, Smith SC Jr, et al
Several developments on the horizon could shape how this combination is studied and potentially applied
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