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These problems also occur with normal B12 levels B12 levels can be altered with a variety of medications including antibiotics, anticonvulsants, birth control pills, cholesterol lowering drugs, and high blood pressure medicine
During pathological conditions like diabetes, COPD, and kidney disease, structural modifications of HSA induced by glucose or acrolein can strongly impair its antioxidant properties
Patients currently on hepatotoxic medications require careful evaluation
Ultimately, the radical chain reactions will be blocked by the antioxidant enzymes superoxide dismutase (SOD) in association with catalase or GPX that determines the complete free radicals scavenging (Winterbourn, 1993)
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