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Weekly injections of 0.6 mL saline (Group 1), 6 mg HA (Group 2), 0.25 mg AOD-9604 (Group 3), and 0.25 mg AOD-9604 with 6 mg HA (Group 4) were administered for 4-7 weeks after the first intra-articular collagenase injection

2 Mechanistic insights into metformins glucose-lowering actions Metformin exerts pleiotropic metabolic effects extending beyond glucose control, notably regulating energy metabolism, autophagy, and redox balance

GHK-Cu at 0.01, 1, and 100 nM incubated with human adult dermal fibroblasts was found to increase production of both collagen and elastin