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This relatively simple structure gave rise to remarkably complex effects on the nervous system

P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model

Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and [PMID: 19288225] Laboratory literature summary: Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may

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