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It is produced using peptide synthesis technology and formulated for controlled administration
Chembiochem (2022) 23(10):e202100641
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The liver was removed and divided, with half fixed in 70% formalin, sectioned, stained with H&E, and the fat content was quantified using Halo 3.6 software
Depletion of cellular GSH by using buthionine sulfoxamine (BSO), which inhibits glutamatecysteine ligase (the rate-limiting enzyme for GSH synthesis) is sufficient to induce ferroptosis due to impaired cellular antioxidant capacity 18
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