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This discrepancy between formal trial data and patient-reported experiences may reflect several factors: cold sensitivity might not have been specifically monitored in trials, it may be attributed to weight loss rather than the medication, or it might affect only a subset of patients
Manfridi A, Forloni GL, Arrigoni-Martelli E, Mancia M
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Its essential to understand that losing weight too quickly is unhealthy and unlikely to be sustainable
