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Phase 2: The Maintenance Phase (Month 3+) As the dose reaches therapeutic levels, more significant benefits become apparent

Patients should also understand that the U.S

With respect to body weight, cotadutide at 200 g led to weight loss of 3.22 kg on average versus 3.33 kg with liraglutide, but the 300 g dose led to weight loss of 5.02 kg albeit with far higher gastrointestinal adverse event rates than liraglutide ( Although cotadutide has progressed well through clinical trials, other GLP-1/glucagon co-agonists have shown mixed results

Unfortunately, its impossible to know the quality and purity of many of the available options

Here are realistic timelines based on the clinical literature and practitioner experience: Weeks 1 to 4: Most users report no visible changes