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Similar content being viewed by others Introduction One rare neurodegenerative disorder with an autosomal recessive inheritance pattern is Wolfram syndrome (WS), which is caused by biallelic mutations of the Wolframin ER transmembrane glycoprotein (Wfs1) gene and first manifests as diabetes mellitus, followed by optic nerve atrophy, deafness, and symptoms of neurodegeneration 1,2,3
Common side effects include nausea (usually mild), decreased appetite (which aids weight loss), mild digestive changes, and occasional stomach discomfort
GLP-1 medications are primarily used to treat type 2 diabetes and assist with weight loss
Adjust the plan based on tolerance and provider guidance
Shridhar, V
