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The main risks are a temporary resurgence of GI side effects (nausea, constipation, diarrhea), temporary appetite suppression reduction during the low-dose titration phase, and a short-term weight loss pause as tirzepatide builds toward therapeutic levels

Second, GLP-1 receptor agonists may slow gallbladder emptying

Tottoli EM, Dorati R, Genta I, Chiesa E, Pisani S, Conti B

Wegovy is approved for long-term use in obese and overweight adults, with clinical trials reporting results after as long as 104 weeks

The study involved a small group of men with an average age of 41 who had been experiencing erectile dysfunction for an average of four years