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The underlying mechanism varies
Relapse to cocaine seeking increases activity-regulated gene expression differentially in the prefrontal cortex of abstinent rats
Archives of Pharmacal Research , 30(7), 834-839
What's happening is pretty straightforward
A significant portion of Americans have embraced freedom of therapeutic choice as a constitutional value for most of the countrys history, Lewis Grossman, a medical historian, writes in his book Choose Your Medicine. Benjamin Rush, a Founding Father and a physician, criticized the medical establishment for being closed-minded about treatments recommended by non-physicians
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