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This review sets out the molecular and central nervous system biology of the GLP-1 receptor, the mechanisms proposed to underlie its neuroprotective effects, and the clinical trial record in Parkinsons and Alzheimers disease
3 Watanabe F, Hashizume E, Chan GP, Kamimura A
This was Citius second try for FDA approval, after the regulator rejected Lymphir in July 2023, outlining the need for enhanced product resting requirements. In its resubmitted data package, the company included findings from the from the Phase III Study 302 trial, where treatment with the drug led to an objective response rate of 36.2%, with 8.7% reaching complete response
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