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In the central nervous system (CNS), during embryogenesis and adulthood, efferocytosis by ramified microglia balances cell death and neurogenesis, ultimately supporting brain development, optimizing neuronal connectivity, and ensuring that inflammatory responses remain appropriate and effective [25, 26]

Although the effects of MMPs on tumor cells vary depending on the specific MMP subtype, tumor type, and patient characteristics, studies indicate that decreased MMP expression is strongly associated with the inhibition of tumor cell metastasis [85, 86]

This ensures that communication can be established easily

Give yourself a plan, support, and time to adjust because tapering off is more than just stopping