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Pro-inflammatory cytokines (e.g., IL-1 and TNF), mediators of Th1 and Th17 cells (e.g., IFN and IL-17), and effector mechanisms involving neutrophils, macrophages, and plasma cells are all implicated in the disease process [28, 29]
But patient access has been a consistent problem because of their cost around $500 a month for higher doses and insurance coverage has been spotty
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Increasing prevalence of type 2 diabetes and healthcare reimbursement and access are some of the major factors which attributed to the boost the growth of the market over the forecast period
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