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Furthermore, TSA (a nonspecific HDAC inhibitor) treatment successfully mimicked the effect of NaB on GLP-1R expression in HepG2 cells, and this finding strongly supported the idea that NaB may affect liver GLP-1 sensitivity through HDAC inhibition
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Funding The research in the authors laboratory was supported by the National Natural Science Foundation of China Grant (No.8217140592, No.81673671) and Special National Key Research and Development Plan (No.2016YFC1306305 J-DX)
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