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The rate of weight regain A 2025 narrative review in the Journal of Clinical Medicine examined weight regain trajectories across multiple GLP-1 receptor agonist studies

And even when you can find them, theres the separate issue of affordability

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However, persistent severe fatigue beyond 8 weeks, worsening depression, or unexplained weakness warrants discussion with your healthcare provider, as this may indicate medication intolerance, inadequate calorie or nutrient intake, or an underlying condition

However, there are reports of an unexpected impact in the bedroom, too