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It also plays a key role in detoxification by binding to harmful substances and facilitating their removal through the liver

& Khler, S

Specifically, 27 studies found a small positive correlation (a slight association between Tylenol use in pregnancy, particularly during the third trimester, and neurodevelopmental conditions) 9 studies found no association 4 studies found a negative association (Tylenol use during pregnancy is correlated with fewer neurodevelopmental conditions) Importantly, each one of the studies in this review was observational, and, therefore, subject to the effects of confounding variables, such as the reasons mothers took Tylenol in the first place, and other factors, such as genetic or environmental exposures

[12] Parenteral choline supports fetal neurodevelopment, yet the safety of supraphysiologic methyl-donor combinations in pregnancy lacks robust evidence

The result is an "energy crisis." In chronic cases, neurons enter a state of metabolic depression they are dormant, "idling" cells [5]